Hitachi and OpGen Agree to Develop Human Chromosome Mapping Analytical Service

Gaithersburg, Md. and Tokyo, Japan-October 16, 2013- OpGen, Inc., a leading genetic analysis company, and Hitachi High-Technologies Corporation today announced an agreement to develop a comprehensive human chromosome mapping analytical service for clinical research applications by a combination of OpGen’s market-leading Whole Genome MappingTM technology and Hitachi High-Technologies’ and Hitachi group’s cloud-based systems. This service will include bioinformatics tools to complete human genome sequence and detect and analyze structural variations in human chromosomes.

“Hitachi High-Technologies Corporation is a global technology leader, and we are pleased to partner with them to create an integrated solution for human genome analysis that captures important structural variation information” said Douglas White, chief executive officer of OpGen, Inc. “The resulting human chromosome mapping service will enable OpGen to continue its expansion into clinical research with the potential to develop diagnostic applications for diseases based on patient’s genetic information.”

Under the terms of this agreement, Hitachi High-Technologies will fund development and the companies will work together to combine the strengths of their proprietary technologies. OpGen’s Whole Genome MappingTM provides a unique view into structural variation in human chromosomes and offers a more accurate and complete analysis of the human genome than next generation sequencing data alone can provide. Many structural variations are associated with cancer, autism, Alzheimer’s disease, and many other cognitive disorders. This type of genetic information will enable development of new therapies, and eventually will empower the broader healthcare community to diagnose and guide treatment decisions based on a patient’s genetic profile.

Hitachi High-Technologies with recognized experience and achievements through DNA sequencer business in life science and translational research market has been developing the cloud platform for human genome data analysis with Hitachi Solutions, in Foster City, California. The human genome cloud platform will enable secure entry portals for researchers, clinicians, and eventually patients to access Whole Genome MappingTM data, human chromosome analytical tools, and ultimately clinically actionable data. As part of the service, Hitachi High-Technologies will also add human DNA sequence analytical tools, which complement Whole Genome MappingTM to provide complete genetic evaluation of human chromosomes.

“This partnership leverages our development of cloud-based informatics platform and provides enabling and proven technology for human genetic analysis,” said Takashi Matsuzaka, senior vice president and executive officer, CTO of Hitachi High-Technologies Corporation. “This is a great example of how Hitachi High-Technologies is continuously enhancing our healthcare informatics offerings for customers worldwide by partnering our technologies with other innovative companies, such as OpGen.”

Hitachi Solutions America, Ltd. will provide cloud infrastructure for Human Chromosome Mapping services and will be attending American Society of Human Genetics Annual Meeting this year from October 22nd through the 26th in Boston. We will discuss the details about the partnership between Hitachi Solutions America, Hitachi High-Technologies and OpGen at ASHG2013 at booth #811. We will also be discussing our cloud-based infrastructure and data-management platform, being called the Human Genome Data Infrastructure. Stop by the booth to qualify for one of these great prizes.

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