DNASIS MAX Features and Benefits

Intuitive, Point-and-Click Sequence Analysis

Execute advanced bioinformatics analyses simply by clicking on the analysis name in the left menu. Multiple analyses can be executed in series, such as translating an open reading frame and analyzing the hydrophilicity/hydrophobicity of its amino acid sequence.

Sequence Input Wizard

A new wizard is displayed when DNASIS® Max is launched, making it easier to create new sequences and import existing sequences from files and databases on your computer or from NCBI.

Advanced Graphical Sequence Editor

Feature annotations in GenBank, PIR, EMBL and Fasta sequence files are automatically displayed graphically in the sequence editor and custom annotations can also be added. Multiple analysis results (e.g. ORF ranges, primer positions) can be displayed, compared and saved as annotations. Individual annotations can be joined to create a new sequence (e.g. to simulate gene splicing). The zoomable Map View lets you interactively explore where analysis results are located relative to other features.

Annotation Editor

Features in GenBank files are automatically displayed and edited. You can also add your own custom annotations. Analysis results(e.g. ORF, primers, protein hydrophilicity) can also be displayed as annotations. You can even join multiple annotations, such as excised regions, to define new sequences.

Adding Comments

Comments can be added to sequences and each analysis result. Annotation data will be automatically imported from GenBank, PIR, EMBL, or Fasta files.

Support for Numerous Sequence File Formats

Sequences in GenBank, Fasta, PIR, EMBL, ABI, SCF, Text and previous DNASIS® sequence formats can be imported. Files containing multiple sequences can also be imported. Sequences and sequence ranges can be exported in Fasta, Simple text or MSF formats. Multiple sequences can either be saved in a single file or in multiple files. 

Display Trace Files from Automated Sequencers

ABI and SCF trace files can be displayed and bases can be edited while looking at traces. Multiple traces can be displayed simultaneously. You can even display opposite strands. Alignments can be performed on the reference sequence and displayed next to the trace, to facilitate identification of SNPs. Vector sequences can be deleted prior to sequence importing for more accurate alignments.

Integrated NCBI Entrez Keyword Search

NCBI's Entrez database can be queried directly from within DNASIS® Max. Individual or multiple sequences can be automatically downloaded from NCBI for editing and analysis.

Support for Projects

Sequences, annotations and analysis results can be saved together in one file as a project. This makes it easier to review the results of time-consuming analyses (e.g. BLAST) without having to repeat them. It also facilitates sharing analysis results with colleagues, and temporarily saving multiple sequences of interest.