(Hitachi Software Engneering America Ltd. MiraiBio Group.)

Hitachi

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Multiplex Expression Analysis with Luminex/Bio-Plex data

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MasterPlex® EX 2010 - Multiplex Expression Data Analysis Software for the Luminex xMAP, Bio-Plex®, and MSD Platforms

MasterPlex EX Detailed Plate View MasterPlex EX Dashboard for Confident Housekeeping Gene Selection
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Powerful support for multiplex expression data analysis by the ONLY software company focused on the Luminex xMAP Platform.

How can MasterPlex EX Benefit You?

  1. Confident Housekeeping Selection

    Choose your Housekeeping Genes with Confidence with 4 new charts at your disposal for Housekeeping Analysis
    1. Control Treatment Chart - View the distribution of MFI or Normalized MFI values of all treatment wells for each given control group.
    2. Well Chart - View the MFI or Normalized MFI values for all selected wells and analytes.
    3. Analyte Comparison - Correlation chart for the MFI or Normalized MFI values between any 2 selected analytes.
    4. Sample MFI Comparison - View the MFI vs. Amount of sample of all selected wells for a given analyte.
  2. Flexible and Fast

    • Have the Freedom to Choose the data you want to display in each well out of 15 possible Data Types and view statiscal data for replicate groups at a glance
      1. MFI
      2. Count
      3. Outlier
      4. Normalized MFI
      5. Fold Change
      6. Sample Name
      7. Group Name
      8. Link Group
      9. MFI Average
      10. MFI Standard Deviation
      11. MFI %CV
      12. Normalized MFI Average
      13. Normalized Standard Deviation
      14. Fold Change Average
      15. Fold Change Standard Deviation

      MasterPlex EX Data Types for Plate View
    • Link multiple Control and Treatment groups with a click of the mouse for fast Fold Change calculations
    • Save your Plate Layout, Control/Treatment links and Housekeeping Gene information to a Template for One-click analysis
  3. Brand New Report Generator

    • Get the report you want your way with our spreadsheet style pivot charts
    • Drag and drop to create your own custom report and export it just about any format

    • MasterPlex QT v4.0 Spreadsheet style pivot charts
  4. Brand New Graphing Engine

    • Create customized publication quality charts and graphs with a few clicks

    • MasterPlex QT v4.0 New highly customizable charting engine
  5. Expand Your Assays

  6. Expand beyond instrument or assay limitations with the Virtual Plate, combining data from two or more real plates to:
    • Increase the "plex" of your experiment
    • Monitor controls over time
    • Calculate fold change across plates

    • MasterPlex EX Virtual Plate
  7. Automatic Outlier Detection

  8. MasterPlex EX helps to make sure you are using reliable data with Automatic Outlier Detection that lets you choose thresholds based on:
    • MFI
    • Count
    • Normalized MFI
    • Fold Change
    • Error Range based on Standard Deviation

    • MasterPlex EX Virtual Plate
  9. Quality Control ManagerNew!

    • Lower Limit of Detection (LLOD) - Automatically calculate your LLOD on a per analyte basis from the mean of the selected background wells plus the number of standard deviations you want defined
    • Percent Coefficient of Variation (% CV) - Define your maximum % CV threshold

    • Quality Control Manager for MasterPlex EX
  10. Completely Redesigned Tabbed UI

    • Simple left to right workflow
    • Context related items grouped in tabs
  11. Import and Setup

  12. Import and parse data from any xMAP based multiplex system. Save time with templates that remember how your samples are arranged on your plates. Mark wells as background, control, treatment and group replicates with a simple click-and-drag.
  13. Navigate

  14. Make sense of large volumes of data with an intuitive interface that replicates the layout of your plates and helps you navigate through each analyte's "layer" of data. View average, standard deviation and CV% for MFI values directly in the plate view without having to run a report.
  15. Calculate

  16. Save time processing data with built-in algorithms that:
    • Calculate fold-change or relative quantification (for gene and microRNA expression profiling) with or without normalization, relative to one or several housekeeping genes.
    • Analyze data from any of the ever-expanding menu of commercially available or in-house developed multiplex assay kits.
  17. Publish and Export

  18. Publish charts and custom reports in any format using highly customizable XSL templates, for easy integration with downstream databases or LIMS.
  19. Share Licenses

  20. Network licensing lets you install MasterPlex EX on as many computers as you need while only paying for software that you actually use.

Reasons to Choose MasterPlex

  • Software is the interface to your experimental results and, more than anything else, is what sets different instrument systems apart. MiraiBio, a Group of Hitachi Software, is the only software company focused on the xMAP platform.

  • MasterPlex protects your investment in an xMAP instrument beyond your current assay needs, because it is regularly updated to support a growing variety of application areas, including chemokine cytokine quantitation, regression analysis, and miRNA and gene expression profiling.
 

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Bio-Plex® is a registered trademark of Bio-Rad Laboratories, Inc.